cái này là nội dung nè hihi Khoa Thuong R&D Services
If you cannot find a molecular diagnostic kit that meets your needs on the market, or if you require support in conducting scientific research projects, please contact Khoa Thuong.
With an experienced R&D team proficient in modern molecular biology techniques, we can meet your requirements with reasonable costs, and we are ready to answer any questions and assist in resolving issues that may arise during the implementation of your research project.
In addition, Khoa Thuong also provides consulting services for establishing molecular biology laboratories, personnel training, and supplying relevant technical documentation.
Selected Research Projects Conducted by Khoa Thuong
Key Ministry-Level Project, VNU-HCM: “Application of molecular biology techniques in the diagnosis of several diseases (Dengue fever, hepatitis B and C, Japanese encephalitis, and Human Papillomavirus (HPV))” (2001–2003).
City-Level Project (Incubation Program – HCMC Department of Science & Technology): “Development of a protocol for detecting and genotyping HPV (Human Papillomavirus)”. Completed 06/2003.
City-Level Project (Incubation Program – HCMC DOST): “Bacterial meningitis: rapid detection of major causative pathogens in cerebrospinal fluid using PCR (Polymerase Chain Reaction) and identification of antibiotic-resistant strains.” Completed 09/2004.
City-Level Project (Biotechnology Program): “Development of a DNA array for detecting meningitis pathogens” (2003–2004).
City-Level Project (Biotechnology Program – HCMC DOST): “Development of a real-time RT-PCR assay for quantification of hepatitis C virus to support research and clinical management” (2004–2005). Completed 2006.
City-Level Project (Medical Program – HCMC DOST): “Application of real-time RT-PCR to quantify hepatitis C virus for treatment indication and monitoring.” (2004–2006), led by the University of Medicine and Pharmacy, HCMC. Completed 2007.
City-Level Project (Medical Program – HCMC DOST): “Investigation of HPV infection in women in Ho Chi Minh City using molecular biology techniques” (2004–2006), led by Hung Vuong Hospital. Completed 2006.
Ministry-Level Project: “Development of PCR and Real-time PCR assays for detection and quantification of Cytomegalovirus (CMV)” (2005–2006). Completed 2006.
City-Level Project (Incubation Program – HCMC DOST): “Detection of basal core promoter and lamivudine-resistant mutations in hepatitis B virus using PCR-RFLP” (2006–2007). Completed 2006.
VNU-HCM Key Scientific Research Project: “Development of a real-time PCR assay for quantifying hepatitis B virus (HBV) in patient blood samples” (2006–2007).
City-Level Pilot Production Project: “Optimization and development of molecular diagnostic kits for HBV, HCV, and HPV detection” (2006–2008).
Key Ministry-Level Project, VNU-HCM: “Production of monoclonal antibodies targeting HPV 18 E6 protein” (2007–2009).
Published Studies:
Nguyen Tuan Anh, Huynh Minh Tuan, Nguyen Van Vinh Chau, Ho Huynh Thuy Duong. Development of the EvaGreen Real-time PCR assay for detection of blaOXA genes in Acinetobacter baumannii. Ho Chi Minh City Medical Journal, Vol. 18, Supplement 5, pp. 197–201, 2014.
Tran Thien Trung et al. Preliminary study on clarithromycin and levofloxacin resistance mutations of Helicobacter pylori using gene sequencing. Vietnam Gastroenterology Science Journal, Vol. IX, No. 37, pp. 2367–2375, 2014.
Tran Thien Trung et al. Diagnostic value of multiplex PCR for Helicobacter pylori compared to CLO-test and serology. Ho Chi Minh City Medical Journal, Vol. 17, Supplement 4, pp. 4–10, 2013.
Tran Thien Trung et al. Analysis of cagA and vacA genes of Helicobacter pylori in gastritis patients using multiplex PCR. Ho Chi Minh City Medical Journal, Vol. 17, Supplement 4, pp. 11–17, 2013.
National-Level Research Collaboration
National Science and Technology Program: “Application of molecular genetics techniques in breeding high-value aquaculture species,” Code KC-04-01 (2002–2004), led by the Institute of Aquaculture I.
Khoa Thuong Biotechnology Co., Ltd. conducted the subproject: “Detection and genetic diversity analysis of White Spot Syndrome Virus (WSSV) and Yellow Head Virus (YHV) using molecular techniques.”
Research Collaboration Agreements
Research collaboration agreement with QUATEST 3: “Evaluation of GMO (Genetically Modified Organism) detection kits using molecular biology techniques” (2013–2014).
Khoa Thuong developed the following kit lines: – AccuPid CaMV 35S Promoter Detection Kit – AccuPid NOS Terminator Detection Kit – AccuPid Maize zSSIIb Detection Kit – AccuPid Soybean Lectin Detection Kit
QUATEST 3 conducted validation and issued official assessment reports.
Additional Scientific Publications
Nguyen Thi My Linh, Ta Dang Khoa, Ho Huynh Thuy Duong. Detection of animal-derived components in vegetarian foods using PCR and Real-time PCR. Journal of Analytical Chemistry, Physics and Biology, Vol. 23, Special Issue No. 5, 2018.
Khoa Thuong’s products have been highly evaluated by customers during application. Several institutions have used the company’s products in their research projects:
“Investigation of HPV infection in women in Ho Chi Minh City using molecular biology techniques” (2004–2006), HCMC DOST, led by Assoc. Prof. Dr. Vu Thi Nhung.
“Application of real-time RT-PCR to quantify hepatitis C virus for treatment monitoring” (2004–2006), HCMC DOST, led by Prof. Dr. Pham Hoang Phiet.
“Preliminary study of clarithromycin and levofloxacin resistance mutations of H. pylori using gene sequencing” (2014), Molecular Diagnostics Center – University Medical Center, HCMC.
“Development of five real-time PCR diagnostic kits for ventilator-associated pneumonia pathogens” (2019), collaboration with Thanh Nhan Hospital.
Nguyen Tuan Anh et al. Overexpression of OXA β-lactamases in carbapenem-resistant Acinetobacter baumannii strains in Southern Vietnam, 2018.
Nguyen Tuan Anh et al. Molecular epidemiology and antimicrobial resistance phenotypes of Acinetobacter baumannii in three hospitals in Southern Vietnam. Journal of Medical Microbiology, Vol. 66, Supplement 1.
Nguyen Tuan Anh et al. Development of a TaqMan real-time PCR assay for detecting blaOXA gene groups in Acinetobacter baumannii. Young Science Bulletin, Vol. 2(1), 2016.
Nguyen Tuan Anh et al. Development and evaluation of a real-time PCR assay for detecting Acinetobacter baumannii. Ho Chi Minh City Medical Journal, Vol. 19, No. 5, 2015.